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Biology 234

Fundamentals of Genetics

Credits: 3

Length of Course: 14 weeks

Classroom Hours per Week: 3 hours lecture, 1 hour tutorial

Prerequisites: Biology 110 or 130, Biology 120, Chemistry 121, and 12 credits

Text: Introduction to Genetic Analysis(11th ed.), Griffiths et al., 2015


Course Description:

This course is an introduction to molecular and classical genetics. Topics include the structure and function of nucleic acids, linkage mapping and pedigree analysis, two gene interactions (codominance, epistasis etc.), gene regulation in prokaryotes and eukaryotes, gene mutations and large scale chromosome re-arrangements, genome and proteome analysis, and population genetics.


Course Outline:

Week Chapter
Week 1 Introduction, genotypes and phenotypes
Week 2 Linkage Mapping
Week 3 Pedigree Analysis
Week 4 Two-Gene Interactions
Week 5 Microbial Genetics
Week 6 DNA and RNA. Protein Synthesis
Week 7 Gene Regulation in Prokaryotes
Week 8 Gene Regulation in Eukaryotes
Week 9 Isolation and Manipulation of DNA
Week 10 Genomics and Proteomics
Week 11 Genetic Mutations, Chromosome re-arrangements
Week 12 Population Genetics
Week 13 Quantitative Genetic Analysis
Week 14 Final Exam

Evaluation:

Quizzes and Tests;       45%

Mid-Term Exam          20%

Final Exam                  35%


Instructors:

J. Greg Doheny, Ph.D., M.Sc., B.Sc. (British Columbia), B.A. (Simon Fraser); RM(CCM)

Rachel Moens, M.Sc. (British Columbia), B.Sc. (McGill)

Todd Harper, Ph.D. (New Brunswick); M.Sc., B.Sc., B.A. (St. Francis Xavier)


Transferability:  see www.bctransferguide.ca